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The incidence of serious adverse occasions with baricitinib treatment, including severe infections, was equivalent to placebo. There have been no opportunistic infections or gastrointestinal perforations in the analysis. An increased incidence of treatment-emergent adverse occasions was noticed with baricitinib compared to placebo. The most common adverse events observed with baricitinib had been headache, upper respiratory system infection and nasopharyngitis. Discontinuation rates due to adverse events were comparable between treatment organizations.